Article
Association between hypertension and the alpha-adducin, beta1-adrenoreceptor, and G-protein beta3 subunit genes in the Japanese population; the Suita study.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jan 2004
Shioji Keisuke, Kokubo Yoshihiro, Mannami Toshifumi, Inamoto Nozomu, Morisaki Hiroko, Mino Yukari, Tagoi Naomi, Yasui Naomi, Iwaii Naoharu
Abstract excerpt
This study focused on 3 genetic polymorphisms that have previously been implicated in hypertension: the alpha-adducin (ADD1/Gly460Trp), beta1-adrenoreceptor (ADRB1/Arg389Gly), and G-protein beta3 subunit (GNB3/C825T) gene polymorphisms. We determined genetic variants using the TaqMan system in a large cohort representing the general population in Japan (867 males, 1,013 females). Logistic analysis indicated that...
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