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Article

Association of GNAS1 gene variant with hypertension depending on smoking status.

Hypertension (Dallas, Tex. : 1979) - 1 Sept 2002

Abe Michiko, Nakura Jun, Yamamoto Miyuki, Jin Ji Jing, Wu Zhihong, Tabara Yasuharu, Yamamoto Yoshikuni, Igase Michiya, Kohara Katsuhiko, Miki Tetsuro

Abstract excerpt

The beta-adrenoceptor (beta-AR) G(s) protein system has been shown to have important roles in the cardiovascular system. The gene encoding the alpha-subunit of G(s) proteins (GNAS1) is a candidate genetic determinant for hypertension. We studied the GNAS1 T393C polymorphism in >2000 Japanese individuals. chi(2) test showed a marginally significant difference in the frequencies of the alleles (P=0.036) and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12215464
DOI: 10.1161/01.hyp.0000028490.77489.0c

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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