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Article

Effect of 393T>C polymorphism of GNAS1 gene on dobutamine response in Chinese healthy subjects.

Journal of clinical pharmacology - 1 Aug 2009

Mao Yan-Mei, Liu Zhao-Qian, Chen Bi-Lian, Guo Dong, Han Chun-Ting, Yang Li-Jun, Wang Sai-Ying, Fan Lan, Zhou Hong-Hao

Abstract excerpt

The purpose of this study was to characterize the functional consequences of the 393T>C polymorphism of the GNAS1 gene in vivo. PCR-RFLP assays were used to identify GNAS1 and beta 1-adrenoceptor genotypes. The heart rate (HR), blood pressure, left ventricular fractional shortening (LVFS), and left ventricular ejection fraction (LVEF) were determined in different genotypes through a modified dobutamine stress...

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Share to Adrenergic beta-Agonists
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Adrenergic, beta-1

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Identifiers

PMID: 19542315
DOI: 10.1177/0091270009337945

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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