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Article

Interaction between GNB3 C825T and ACE I/D polymorphisms in essential hypertension in Koreans.

Journal of human hypertension - 1 Feb 2007

Bae Y, Park C, Han J, Hong Y-J, Song H-H, Shin E-S, Lee J-E, Han B-G, Jang Y, Shin D-J, Yoon S K

Abstract excerpt

Essential hypertension (EH) is considered a typical polygenic disease, so the evaluation of gene-gene interactions rather than the determination of single gene effects is crucial to understanding any genetic influences. The G-protein beta3-subunit (GNB3) 825T allele, associated with enhanced G-protein signalling, is a strong candidate for interactions with polymorphisms, such as insertion/deletion (I/D)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17066084
DOI: 10.1038/sj.jhh.1002110

Genes

ACE
GNB3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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