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Article

The interaction of AGT and NOS3 gene polymorphisms with conventional risk factors increases predisposition to hypertension.

Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2013

Gatti Renata R, Santos Paula S, Sena Angela A S, Marangoni Karina, Araújo Messias A, Goulart Luiz R

Abstract excerpt

Renin-angiotensin and kallikrein-kinin systems are interconnected, regulating blood pressure homeostasis. We have demonstrated the interactions among polymorphisms of the angiotensinogen (AGT) and endothelial nitric oxide synthase (NOS3) genes and conventional risk factors affecting the hypertension occurrence. Individuals were recruited (n=192) and classified into hypertensive (HG; n=140) and normotensive (NG;...

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Source

Identifiers

PMID: 22791701
DOI: 10.1177/1470320312452027

Genes

AGT
NOS3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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