Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interest of tumor necrosis factor-alpha -308 G/A and interleukin-10 -592 C/A polymorphisms in human African trypanosomiasis.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Mar 2006

Courtin David, Argiro Laurent, Jamonneau Vincent, N'dri Louis, N'guessan Paul, Abel Laurent, Dessein Alain, Cot Michel, Laveissiere Claude, Garcia André

Abstract excerpt

This study aimed to determine whether single nucleotide polymorphisms (SNPs) within tumour necrosis factor-alpha (TNF) and interleukin-10 (IL10) promoters and genes are associated with human African trypanosomiasis (HAT). The polymorphisms used in the analysis were TNF(-308G/A), TNF(-238G/A), TNF(-1031T/C), TNF(+488G/A), IL10(-1082G/A) and IL10(-592C/A). A familial case-control sample of 277 individuals (102...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chi-Square Distribution
Share to Family

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homozygote

Share to Interleukin-10

Share to Logistic Models

Share to Promoter Regions, Genetic

Share to Trypanosomiasis, African

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 15894515
DOI: 10.1016/j.meegid.2005.03.002

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interest of tumor necrosis factor-alpha -308 G/A and interleukin-10 -592 C/A polymorphisms in human African trypanosomiasis.PMID 15894515Read ↗

[Human African trypanosomiasis: involvement of host genetics].Semantic proximity Read ↗

TNF-α -238, -308, -863 polymorphisms, and brucellosis infection.Semantic proximity Read ↗

Interleukin-10 and tumor necrosis factor-alpha gene polymorphisms in tuberculosis.Semantic proximity Read ↗

Association of tumor necrosis factor-alpha-308 (G-->A) polymorphism and susceptibility to brucellosis.Semantic proximity Read ↗

Genetic and functional role of TNF-alpha in the development Trypanosoma cruzi infection.Semantic proximity Read ↗

TNFA promoter polymorphism and susceptibility to brucellosis.Semantic proximity Read ↗

Association of tumor necrosis factor alpha and IL-10 promoter polymorphisms with rheumatoid arthritis in North Indian population.Semantic proximity Read ↗

Tumor necrosis factor alpha -308 gene locus promoter polymorphism: an analysis of association with health and disease.Semantic proximity Read ↗

Genetic, epidemiological and biological analysis of interleukin-10 promoter single-nucleotide polymorphisms suggests a definitive role for -819C/T in leprosy susceptibility.Semantic proximity Read ↗

Association between the IL-10-1082G/A, IL-10-819T/C and IL-10-592A/C polymorphisms and Brucellosis susceptibility: a meta-analysis.Semantic proximity Read ↗

Alleles -308A and -1031C in the TNF-alpha gene promoter do not increase the risk but associated with circulating levels of TNF-alpha and clinical features of vivax malaria in Indian patients.Semantic proximity Read ↗

Association of TNF -1031 C/C as a potential protection marker for leprosy development in Amazonas state patients, Brazil.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.