Article
Association of tumor necrosis factor alpha and IL-10 promoter polymorphisms with rheumatoid arthritis in North Indian population.
Rheumatology international - 1 Jul 2010
Gambhir Deepali, Lawrence Able, Aggarwal Amita, Misra Ramnath, Mandal Sudhir Kumar, Naik Sita
Abstract excerpt
Rheumatoid arthritis is a chronic autoimmune disorder associated with altered expression of pro- and anti-inflammatory cytokines in the affected tissues. The aim of this study was to investigate the association between promoter polymorphisms of TNFalpha and IL-10 gene with susceptibility, age of disease onset and disease severity in North Indian patients with rheumatoid arthritis (RA). SNPs at position -308 and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
