Article
Interleukin-10 and tumor necrosis factor-alpha gene polymorphisms in tuberculosis.
Journal of clinical immunology - 1 May 2008
Ates O, Musellim B, Ongen G, Topal-Sarikaya A
Abstract excerpt
Tuberculosis (TB), caused by Mycobacterium tuberculosis, is an infectious disease in humans killing nearly three million people and eight million cases annually. The cytokines TNF-alpha and IL-10 have been implicated in the pathogenesis of TB. Certain single nucleotide polymorphisms within the promoter region of the IL10 and TNF genes have been associated with altered levels of circulating IL10 and TNF-alpha. We...
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