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Article

Genetic and functional role of TNF-alpha in the development Trypanosoma cruzi infection.

PLoS neglected tropical diseases - 8 Mar 2011

Pissetti Cristina Wide, Correia Dalmo, de Oliveira Rafael Faria, Llaguno Maurício Manoel, Balarin Marly Aparecida Spadotto, Silva-Grecco Roseane Lopes, Rodrigues Virmondes

Abstract excerpt

TNF-alpha plays an important role in trypanocidal mechanisms and is related to tissue injury. This cytokine has been detected in the heart of human chagasic patients where it is associated with tissue damage. This study investigated whether TNF-alpha levels and the presence of genetic polymorphis...

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Source

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Identifiers

PMID: 21408088
DOI: 10.1371/journal.pntd.0000976
PMCID: PMC3050938

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21408088-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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