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Article

Association of TNF -1031 C/C as a potential protection marker for leprosy development in Amazonas state patients, Brazil.

Human immunology - 1 Mar 2015

Silva G A V, Ramasawmy R, Boechat A L, Morais A C, Carvalho B K S, Sousa K B A, Souza V C, Cunha M G S, Barletta-Naveca R H, Santos M P, Naveca F G

Abstract excerpt

Polymorphisms present in the TNF promoter region has shown to influence the gene transcription. Leprosy displays different clinical manifestations according to the immune responses of the individual infected with Mycobacterium leprae. In this study, we evaluated the single nucleotide polymorphisms (SNPs) -238 G/A (rs361525), -308 G/A (rs1800629), -857 C/T (rs1799724), -863 A/C (rs1800630) and -1031 T/C...

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Source

Identifiers

PMID: 25636570
DOI: 10.1016/j.humimm.2015.01.011

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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