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Article

A dual-probe hybridization method for reducing variability in single nucleotide polymorphism analysis with oligonucleotide microarrays.

Analytical biochemistry - 15 Dec 2008

Yin Bin-Cheng, Li Honghua, Ye Bang-Ce

Abstract excerpt

DNA microarray technology has become powerful and popular in mutation/single nucleotide polymorphism (SNP) discovery and genotyping. However, this method is often associated with considerable signal noise of nonbiological origin that may compromise the data quality and interpretation. To achieve a high degree of reliability, accuracy, and sensitivity in data analysis, an effective normalization method to minimize...

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PMID: 18817743
DOI: 10.1016/j.ab.2008.09.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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