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Article

Single-molecule dilution and multiple displacement amplification for molecular haplotyping.

BioTechniques - 1 Apr 2005

Paul Philip, Apgar Josh

Abstract excerpt

Separate haploid analysis is frequently required for heterozygous genotyping to resolve phase ambiguity or confirm allelic sequence. We demonstrate a technique of single-molecule dilution followed by multiple strand displacement amplification to haplotype polymorphic alleles. Dilution of DNA to haploid equivalency, or a single molecule, is a simple method for separating di-allelic DNA. Strand displacement...

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PMID: 15884673
DOI: 10.2144/05384ST01

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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