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Article

Mutation and haplotype analysis for Duchenne muscular dystrophy by single cell multiple displacement amplification.

Molecular human reproduction - 1 Jun 2007

Ren Zi, Zhou Canquan, Xu Yanwen, Deng Jie, Zeng Haitao, Zeng Yanhong

Abstract excerpt

Duchenne muscular dystrophy (DMD) is an X-linked recessive genetic disorder with mutational heterogeneity. The scarcity of DNA from single cells in preimplantation genetic diagnosis (PGD) for DMD limits comprehensive genetic testing. Multiple displacement amplification (MDA) is reported to generate large amounts of template and give the most complete coverage and unbiased amplification to date. Here, we developed...

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Source

Identifiers

PMID: 17439955
DOI: 10.1093/molehr/gam020

Genes

DMD
PGD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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