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ADLAPH: A molecular haplotyping method based on allele-discriminating long-range PCR.

Genomics - 1 Sept 2004

Yu Chang-En, Devlin Bernie, Galloway Nichole, Loomis Elaine, Schellenberg Gerard D

Abstract excerpt

We present a method, called Allele-Discriminating Long and Accurate PCR Haplotyping (ADLAPH), for directly determining haplotypes from an extended genomic region. This method uses allele-discriminating primers in long-range PCR to amplify only one of the two chromosome homologues for the region of interest. Haplotypes are then determined from these phase-separated PCR fragments by conventional single nucleotide...

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PMID: 15498468
DOI: 10.1016/j.ygeno.2004.06.003

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APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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