Article
The neurotrophin receptor p75NTR modulates long-term depression and regulates the expression of AMPA receptor subunits in the hippocampus.
Proceedings of the National Academy of Sciences of the United States of America - 17 May 2005
Rösch Harald, Schweigreiter Rüdiger, Bonhoeffer Tobias, Barde Yves-Alain, Korte Martin
Abstract excerpt
Neurotrophins are involved in the modulation of synaptic transmission, including the induction of long-term potentiation (LTP) through the receptor TrkB. Because previous studies have revealed a bidirectional mode of neurotrophin action by virtue of signaling through either the neurotrophin receptor p75NTR or the Trk receptors, we tested the hypothesis that p75NTR is important for longterm depression (LTD) to...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
