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Article

TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Sept 1998

Martínez A, Alcántara S, Borrell V, Del Río J A, Blasi J, Otal R, Campos N, Boronat A, Barbacid M, Silos-Santiago I, Soriano E

Abstract excerpt

Recent studies have suggested a role for neurotrophins in the growth and refinement of neural connections, in dendritic growth, and in activity-dependent adult plasticity. To unravel the role of endogenous neurotrophins in the development of neural connections in the CNS, we studied the ontogeny of hippocampal afferents in trkB (-/-) and trkC (-/-) mice. Injections of lipophilic tracers in the entorhinal cortex...

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PMID: 9736654
PMCID: PMC6793248

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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