Article
TrkB and TrkC signaling are required for maturation and synaptogenesis of hippocampal connections.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 15 Sept 1998
Martínez A, Alcántara S, Borrell V, Del Río J A, Blasi J, Otal R, Campos N, Boronat A, Barbacid M, Silos-Santiago I, Soriano E
Abstract excerpt
Recent studies have suggested a role for neurotrophins in the growth and refinement of neural connections, in dendritic growth, and in activity-dependent adult plasticity. To unravel the role of endogenous neurotrophins in the development of neural connections in the CNS, we studied the ontogeny...
Topics
- Animals
- Antigens, Surface
- Calcium-Binding Proteins
- Entorhinal Cortex
- Female
- Gene Expression Regulation, Developmental
- Hippocampus
- Male
- Membrane Glycoproteins
- Membrane Proteins
- Mice
- Mice, Knockout
- Nerve Tissue Proteins
- Neural Pathways