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Article

Complete deletion of the neurotrophin receptor p75NTR leads to long-lasting increases in the number of basal forebrain cholinergic neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Apr 2002

Naumann Thomas, Casademunt Elisabeth, Hollerbach Ewald, Hofmann Jutta, Dechant Georg, Frotscher Michael, Barde Yves-Alain

Abstract excerpt

Cholinergic neurons innervating cortical structures are among the most affected neuronal populations in Alzheimer's disease. In rodents, they express high levels of the neurotrophin receptor p75NTR. We have analyzed cholinergic septohippocampal neurons of the medial septal nucleus in p75exonIII (partial p75NTR knock-out) and p75exonIV (complete p75NTR knock-out) mice, in their original genetic background and in...

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PMID: 11923404
PMCID: PMC6758339

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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