Article
Allelic diversity at the primate major histocompatibility complex DRB6 locus.
Immunogenetics - 1 Jan 1992
Corell A, Morales P, Varela P, Paz-Artal E, Martin-Villa J M, Martinez-Laso J, Arnaiz-Villena A
Abstract excerpt
The HLA-DRB6 gene (also called DRB sigma/V1) has been found only in about 26% of human HLA haplotypes, i.e.; DR1, DRw10, and DR2-bearing ones (Corell et al. 1991). In contrast, exon-2 DRB6 sequences have been obtained from all tested primates: nine chimpanzees (Pan troglodytes), three gorillas (Gorilla gorilla) and three orangutans (Pongo pygmaeus); other apes which had already been sequenced (one gorilla and one...
Topics
- Alleles
- Animals
- Base Sequence
- Biological Evolution
- Genes, MHC Class II
- HLA-DR Antigens
- HLA-DR beta-Chains
- Humans
- Major Histocompatibility Complex
- Molecular Sequence Data
- Polymorphism, Genetic
