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Article

Estimation of the species-specific mutation rates at the DRB1 locus in humans and chimpanzee.

Tissue antigens - 1 Nov 2006

Ohashi J, Naka I, Toyoda A, Takasu M, Tokunaga K, Ishida T, Sakaki Y, Hohjoh H

Abstract excerpt

To estimate the species-specific mutation rates at the DRB1 locus in humans and chimpanzee, we analyzed the nucleotide sequence of a 37.6-kb chimpanzee chromosomal segment containing the entire Patr-DRB1*0701 allele and the flanking nongenic region and we compared it with two corresponding human sequences containing the HLA-DRB1*070101 allele using the sequence of HLA-DRB1*04011 as an outgroup. Because the...

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Identifiers

PMID: 17092256
DOI: 10.1111/j.1399-0039.2006.00688.x

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Source receipt: pubmed, retrieved 7 Sept 2026.

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