Article
The chimpanzee Mhc-DRB region revisited: gene content, polymorphism, pseudogenes, and transcripts.
Molecular immunology - 1 Dec 2009
de Groot Natasja G, Heijmans Corrine M C, de Groot Nanine, Doxiadis Gaby G M, Otting Nel, Bontrop Ronald E
Abstract excerpt
In humans, great apes, and different monkey species, the major histocompatibility complex (MHC) class II DRB region is known to display considerable copy number variation. The microsatellite D6S2878 has been shown to be a valuable marker for haplotyping the DR region in humans and macaque species. The present report illustrates that chimpanzee haplotypes also can be discriminated with this marker. The analyses...
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