Article
Extensive DRB region diversity in cynomolgus macaques: recombination as a driving force.
Immunogenetics - 1 Mar 2010
Doxiadis Gaby G M, de Groot Nanine, de Groot Natasja G, Rotmans Gabriëlle, de Vos-Rouweler Annemiek J M, Bontrop Ronald E
Abstract excerpt
The DR region of primate species is generally complex and displays diversity concerning the number and combination of distinct types of DRB genes present per region configuration. A highly variable short tandem repeat (STR) present in intron 2 of nearly all primate DRB genes can be utilized as a quick and accurate high through-put typing procedure. This approach resulted previously in the description of unique...
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