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Article

Shared polymorphism between gorilla and human major histocompatibility complex DRB loci.

Human immunology - 1 Aug 1992

Kupfermann H, Mayer W E, O'hUigin C, Klein D, Klein J

Abstract excerpt

A high degree of polymorphism and high nucleotide diversity mark the functional genes of the major histocompatibility complex (Mbc). Alleles at the different Mbc loci can be classified into distinct lineages that are shared between species and, therefore, are presumed to have been founded before speciation. We have sequenced the most polymorphic part of 25 gorilla Mbc-DRB genes from six individuals. (The DRB...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Consensus Sequence
DNA
Female
Genetic Linkage
Gorilla gorilla
HLA-DR Antigens
Humans
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Polymerase Chain Reaction

Polymorphism, Genetic

Source

Identifiers

PMID: 1464555
DOI: 10.1016/0198-8859(92)90026-j

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1464555-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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