Article
Mhc-DRB diversity of the chimpanzee (Pan troglodytes).
Immunogenetics - 1 Jan 1992
Kenter M, Otting N, Anholts J, Jonker M, Schipper R, Bontrop R E
Abstract excerpt
Fifty-four chimpanzee Patr-DRB and five human HLA-DRB second exons were cloned and sequenced from thirty-five chimpanzees and four human B-cell lines and compared with known Mhc-DRB sequences of these two species. Equivalents of the HLA-DRB1*02, -DRB1*03, -DRB1*07 allelic lineages and the HLA-DRB3, -DRB4, -DRB5, -DRB6, and -DRB7 loci were all found in the chimpanzee. In addition, two chimpanzee Patr-DRB lineages...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Biological Evolution
- Cell Line
- Cloning, Molecular
- DNA
- Exons
- Genetic Variation
- HLA-DR Antigens
- Hominidae
- Humans
