Article
Low mutational rate of K-ras codon 12 in singular bronchoscopy specimens in suspected lung cancer.
Neoplasma - 1 Jan 2005
Spasova I, Novotna H, Vachtenheim J, Bartosova H, Patek J, Hoserova V, Zatloukal P, Kinkor Z
Abstract excerpt
Mutations of the K-ras gene are found in a subset of non-small- cell lung carcinomas (NSCLC). The aim of our study was to determine the K-ras codon 12 mutation in the first, singular bronchoscopy specimen in parallel with the cytological examination for the diagnosis of lung cancer. Samples were obtained by diagnostic bronchoscopy in 140 patients with suspected lung tumors. The analysis of K-ras mutations was...
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