Article
Detection of K-ras mutations of bronchoalveolar lavage fluid cells aids the diagnosis of lung cancer in small pulmonary lesions.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Mar 1999
Oshita F, Nomura I, Yamada K, Kato Y, Tanaka G, Noda K
Abstract excerpt
An increased prevalence of K-ras oncogene mutation in lung adenocarcinoma has been shown by PCR-primer-introduced restriction with enrichment for mutation alleles (PCR-PIREMA) experiments. In the present study we investigated whether this method is useful for the diagnosis of lung cancer in small pulmonary lesions, which are difficult to diagnose cytologically as lung cancer by bronchoscopic examination. We...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
