Article
Increased prevalence of K-ras oncogene mutations in lung adenocarcinoma.
Cancer research - 1 Apr 1995
Mills N E, Fishman C L, Rom W N, Dubin N, Jacobson D R
Abstract excerpt
Reported estimates of ras mutation prevalence in lung adenocarcinoma of 15-24% may be underestimates because of the insensitivity of the assays used. We have devised a rapid, non-radioactive assay for ras mutations, which detects 1 mutant allele/10(3) normal alleles and have used it to study DNA isolated from 53 lung tumor samples (including 28 adenocarcinomas) previously analyzed by PCR/allele specific...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
