Article
Detection of K-ras gene mutations in non-neoplastic lung tissue and lung cancers.
Cancer letters - 15 May 1996
Nelson M A, Wymer J, Clements N
Abstract excerpt
Oncogene and tumor suppressor gene mutations are candidate biomarkers for cancer risk assessment and lesion detection. The K-ras oncogene has previously been associated with non-small cell lung cancer (NSCLC), particularly adenocarcinomas in which reported rates of mutation have approached 30-40%. We have analyzed non-malignant lung tissue from patients with lung cancer and primary lung cancers for K-ras gene...
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