Article
A multifunctional domain of the calcium-responsive transactivator (CREST) that inhibits dendritic growth in cultured neurons.
The Journal of biological chemistry - 1 Jul 2005
Pradhan Anuradha, Liu Yuechueng
Abstract excerpt
The calcium-responsive transactivator (CREST) is targeted to nuclear bodies and is required for the normal development of neuronal dendritic trees. Here we report the identification of a multifunctional domain (MFD) of CREST that is involved in transcription transactivation, nuclear body targeting, and dimerization. MFD is located near the C terminus of CREST from amino acid 251 to 322 and is required and...
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