Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Regulation of dendritic development by BDNF requires activation of CRTC1 by glutamate.

The Journal of biological chemistry - 10 Sept 2010

Finsterwald Charles, Fiumelli Hubert, Cardinaux Jean-René, Martin Jean-Luc

Abstract excerpt

Dendritic growth is essential for the establishment of a functional nervous system. Among extrinsic signals that control dendritic development, substantial evidence indicates that BDNF regulates dendritic morphology. However, little is known about the underlying mechanisms by which BDNF controls dendritic growth. In this study, we show that the MAPK signaling pathway and the transcription factor cAMP response...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glutamic Acid
Share to Active Transport, Cell Nucleus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Brain-Derived Neurotrophic Factor

Share to Cyclic AMP Response Element-Binding Protein

Share to Dendrites

Share to Gene Knockdown Techniques

Share to MAP Kinase Signaling System

Share to Rats, Sprague-Dawley

Source

Open in PubMed Open full text

Identifiers

PMID: 20639200
DOI: 10.1074/jbc.M110.125740
PMCID: PMC2937884

Genes

BDNF
CRTC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Regulation of dendritic development by BDNF requires activation of CRTC1 by glutamate.PMID 20639200Read ↗

Regulation of cortical dendrite development by Rap1 signaling.Semantic proximity Read ↗

Dendritic structural plasticity and neuropsychiatric disease.Semantic proximity Read ↗

CRMP4 regulates dendritic growth and maturation via the interaction with actin cytoskeleton in cultured hippocampal neurons.Semantic proximity Read ↗

The expression level of CACNA1C-encoded Ca <sub>V</sub> 1.2 is a tipping point between promotion and inhibition of dendritic growth in neuronsSemantic proximity Read ↗

Beta-catenin is critical for dendritic morphogenesis.Semantic proximity Read ↗

Zipcode binding protein 1 regulates the development of dendritic arbors in hippocampal neurons.Semantic proximity Read ↗

[Abnormal dendritic spine morphology and its signal transduction mechanisms in mental retardation].Semantic proximity Read ↗

Early disruption of the CREB pathway drives dendritic morphological alterations in FTD/ALS cortical neuronsSemantic proximity Read ↗

NMDA receptor subunit composition controls dendritogenesis of hippocampal neurons through CAMKII, CREB-P, and H3K27ac.Semantic proximity Read ↗

Doublecortin-like kinase enhances dendritic remodelling and negatively regulates synapse maturation.Semantic proximity Read ↗

GABA-cAMP response element-binding protein signaling regulates maturation and survival of newly generated neurons in the adult hippocampus.Semantic proximity Read ↗

CREB selectively controls learning-induced structural remodeling of neurons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.