Article
Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.
Science (New York, N.Y.) - 9 Jan 2004
Aizawa Hiroyuki, Hu Shu-Ching, Bobb Kathryn, Balakrishnan Karthik, Ince Gulayse, Gurevich Inga, Cowan Mitra, Ghosh Anirvan
Abstract excerpt
The lasting effects of neuronal activity on brain development involve calcium-dependent gene expression. Using a strategy called transactivator trap, we cloned a calcium-responsive transactivator called CREST (for calcium-responsive transactivator). CREST is a SYT-related nuclear protein that int...
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