Article
Role of a CYP17 promoter polymorphism for familial prostate cancer risk in Germany.
Anticancer research - 1 Jan 2000
Vesovic Zorica, Herkommer Kathleen, Vogel Walther, Paiss Thomas, Maier Christiane
Abstract excerpt
BACKGROUND: A thymidine to cytosine transition (designated A2 variant) in the promoter region of CYP17 has previously been associated with a familial history of prostate cancer in North American families. The purpose of the present study was to determine whether this correlation could be replicated in a European population. MATERIALS AND METHODS: Case-control comparisons were performed by modelling a dominant...
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