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Article

CYP17 gene polymorphism and prostate cancer susceptibility in a Tunisian population.

Cancer epidemiology - 1 Oct 2011

Souiden Yousra, Mahdouani Manel, Chaieb Kamel, Elkamel Rafik, Mahdouani Kacem

Abstract excerpt

Prostate cancer (PCa) formation has been reported to be associated with androgen. Two key steps in the sex steroid synthesis are mediated by the enzyme cytochrome P450c 17α which is encoded in the CYP17 gene. The A2 allele of the CYP17 gene has been thought to be associated with increased functional activity of this steroidogenic enzyme. Consequently, the A2 allele has been examined as a biomarker of individual...

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Identifiers

PMID: 21193363
DOI: 10.1016/j.canep.2010.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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