Article
A polymorphism in the CYP17 gene and risk of prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2002
Stanford Janet L, Noonan Elizabeth A, Iwasaki Lori, Kolb Suzanne, Chadwick Robert B, Feng Ziding, Ostrander Elaine A
Abstract excerpt
Steroid hormones are important in the etiology and progression of prostate cancer, and expression of genes involved in hormone production may alter susceptibility. One such gene is CYP17, which encodes the cytochrome P450c17a enzyme responsible for the biosynthesis of testosterone. A T to C trans...
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