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Article

Polymorphism in the Androgen Biosynthesis Gene (CYP17), a Risk for Prostate Cancer: A Meta-Analysis.

American journal of men's health - 1 Jan 2000

Effah Clement Yaw, Wang Ling, Agboyibor Clement, Drokow Emmanuel Kwateng, Yu Songcheng, Wang Wei, Wu Yongjun

Abstract excerpt

Gene polymorphism is one of the few factors that increases the risk of prostate cancer. T to C substitution in the 5' promoter region of the CYP17 gene is hypothesized to increase the rate of gene transcription, increase androgen production, and thereby increase the risk of prostate cancer. Nevertheless, the inconsistencies originating from studies on CYP17 polymorphism and prostate cancer prompted this...

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Androgens
Genotype
Polymorphism, Genetic
Prostatic Neoplasms
Risk Assessment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Steroid 17-alpha-Hydroxylase

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PMID: 32964792
DOI: 10.1177/1557988320959984
PMCID: PMC7518003

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Polymorphism in the Androgen Biosynthesis Gene (CYP17), a Risk for Prostate Cancer: A Meta-Analysis.PMID 32964792Read ↗

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