Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Prostate cancer associated with CYP17 genotype.

Pharmacogenetics - 1 Oct 1999

Wadelius M, Andersson A O, Johansson J E, Wadelius C, Rane E

Abstract excerpt

Androgens play an important role in the development of prostate cancer. Androgen regulating genes that show allelic variation may be susceptibility factors for the disease. One of these genes, CYP17, encodes the cytochrome P450c17alpha enzyme. It catalyses steroid 17alpha-hydroxylase/17,20 lyase activities at key points in testosterone biosynthesis. We investigated the association between a polymorphism in the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA Primers
Share to Pharmacogenetics
Share to Polymorphism, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Prostatic Neoplasms

Share to Risk Factors

Share to Androgens

Share to Case-Control Studies

Share to Steroid 17-alpha-Hydroxylase

Source

Identifiers

PMID: 10591544

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Prostate cancer associated with CYP17 genotype.PMID 10591544Read ↗

A polymorphism in the CYP17 gene and risk of prostate cancer.Semantic proximity Read ↗

A polymorphism in the CYP17 gene is associated with prostate cancer risk.Semantic proximity Read ↗

Polymorphism in the Androgen Biosynthesis Gene (CYP17), a Risk for Prostate Cancer: A Meta-Analysis.Semantic proximity Read ↗

CYP17 polymorphisms in relation to risks of prostate cancer and benign prostatic hyperplasia: a population-based study in China.Semantic proximity Read ↗

Association of the CYP17 gene polymorphism with the risk of prostate cancer: a meta-analysis.Semantic proximity Read ↗

CYP17 gene polymorphism and prostate cancer susceptibility in a Tunisian population.Semantic proximity Read ↗

A2 allele polymorphism of the CYP17 gene and prostate cancer risk in an iranian population.Semantic proximity Read ↗

Cyp17 genetic polymorphism in prostate cancer and benign prostatic hyperplasia.Semantic proximity Read ↗

The role of CYP17A1 in prostate cancer development: structure, function, mechanism of action, genetic variations and its inhibition.Semantic proximity Read ↗

Relationship between CYP17 gene polymorphisms and risk of prostate cancer.Semantic proximity Read ↗

CYP17 gene polymorphism and its association in north Indian prostate cancer patients.Semantic proximity Read ↗

Germ-line genetic variation in the key androgen-regulating genes androgen receptor, cytochrome P450, and steroid-5-alpha-reductase type 2 is important for prostate cancer development.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.