Article
CYP17 gene polymorphism and its association in north Indian prostate cancer patients.
Anticancer research - 1 May 2009
Sobti Ranbir Chander, Gupta Lipsy, Thakur Hitender, Seth Amlesh, Singh Sharwan K, Kaur Pushpinder
Abstract excerpt
BACKGROUND: The CYP17 gene codes for the cytochrome P450c17a enzyme, which mediates two key steps in sex steroid synthesis In this study, the association between CYP17 polymorphism and the risk of prostate cancer in comparison to benign prostatic hyperplasia (BPH) in a north Indian population was investigated. PATIENTS AND METHODS: This study included 157 prostate cancer patients and 170 BPH patients as controls....
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