Article
Association of human hippocampal neurochemistry, serotonin transporter genetic variation, and anxiety.
NeuroImage - 15 May 2005
Gallinat Jürgen, Ströhle Andreas, Lang Undine E, Bajbouj Malek, Kalus Peter, Montag Christiane, Seifert Frank, Wernicke Catrin, Rommelspacher Hans, Rinneberg Herbert, Schubert Florian
Abstract excerpt
The impact of the serotonin transporter (5-HTT) gene-linked polymorphic region (5-HTTLPR) on anxiety-related behavior and related cerebral activation has facilitated the understanding of neurobiological mechanisms of anxiety. However, the influence of the 5-HTTLPR genotype on hippocampal neuronal development and neurochemistry, which is relevant to anxiety behavior, has not been investigated. In 38 healthy...
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