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Article

Association of human hippocampal neurochemistry, serotonin transporter genetic variation, and anxiety.

NeuroImage - 15 May 2005

Gallinat Jürgen, Ströhle Andreas, Lang Undine E, Bajbouj Malek, Kalus Peter, Montag Christiane, Seifert Frank, Wernicke Catrin, Rommelspacher Hans, Rinneberg Herbert, Schubert Florian

Abstract excerpt

The impact of the serotonin transporter (5-HTT) gene-linked polymorphic region (5-HTTLPR) on anxiety-related behavior and related cerebral activation has facilitated the understanding of neurobiological mechanisms of anxiety. However, the influence of the 5-HTTLPR genotype on hippocampal neuronal...

Topics

Alleles
Anxiety
Aspartic Acid
Biomarkers
DNA
Genotype
Gyrus Cinguli
Hippocampus
Humans
Magnetic Resonance Imaging
Membrane Glycoproteins
Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nerve Tissue Proteins

Psychiatric Status Rating Scales

Serotonin Plasma Membrane Transport Proteins

Synapses

Source

Identifiers

PMID: 15862212
DOI: 10.1016/j.neuroimage.2005.01.001

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15862212-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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