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Article

Smaller hippocampus volume is associated with short variant of 5-HTTLPR polymorphism in medication-free major depressive disorder patients.

Neuropsychobiology - 1 Jan 2011

Eker M Cagdas, Kitis Omer, Okur Hamza, Eker Ozlem Donat, Ozan Erol, Isikli Serhan, Akarsu Nurten, Gonul Ali Saffet

Abstract excerpt

AIM: Serotonin is known for its importance in the pathophysiology of major depressive disorder. Although the hippocampus is one of the key regions in which neurogenesis occurs, and serotonin plays an important role in neurogenesis, results of studies that investigate effect of the 5-HTTLPR polymorphism on hippocampal volumes in major depressive disorder are inconclusive. METHOD: We looked for a relationship...

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PMID: 20962544
DOI: 10.1159/000321834

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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