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Article

Structural and functional imaging of the hippocampus in young people at familial risk of depression.

Psychological medicine - 1 Oct 2014

Mannie Z N, Filippini N, Williams C, Near J, Mackay C E, Cowen P J

Abstract excerpt

BACKGROUND: Major depression is associated with abnormalities in the function and structure of the hippocampus. However, it is unclear whether these abnormalities might also be present in people 'at risk' of illness. METHOD: We studied 62 young people (mean age 18.8 years) at familial risk of depression (FH+) but who had never been depressed themselves. Participants underwent magnetic resonance imaging to assess...

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Identifiers

PMID: 25066547
DOI: 10.1017/S0033291714000580

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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