Article
Differential roles of XRCC2 in homologous recombinational repair of stalled replication forks.
Journal of cellular biochemistry - 1 Aug 2005
Liu Nan, Lim Chang-Su
Abstract excerpt
Homologous recombination is an important mechanism in DNA replication to ensure faithful DNA synthesis and genomic stability. In this study, we investigated the role of XRCC2, a member of the RAD51 paralog family, in cellular recovery from replication arrest via homologous recombination. The protein expression of XRCC2, as well as its binding partner RAD51D, is dramatically increased in S- and G2-phases,...
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