Article

SMARCAL1: a DNA repair protein recruited to double-strand breaks at stalled replication forks to promote genome stability through a homologous recombination pathway

2024-10-30

Abstract excerpt

<title>Abstract</title> <p>To create an exact copy of the entire genome, replication should be completed promptly and accurately. However, obstacles can arise during replication that can cause genotoxic fork stalling. The DNA damage response pathway plays a crucial role in preventing fork collapse by stabilizing the stalled fork, regulating DNA repair, and promoting replication restart. There are multiple pathway...

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Literature Corpus work: cd159622-aa5d-5c04-898a-f9574225f0a6
DOI: 10.21203/rs.3.rs-5281240/v1

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