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Article

Association between beta-1 and beta-2 adrenergic receptor gene polymorphisms and the response to beta-blockade in patients with stable congestive heart failure.

Pharmacogenetics and genomics - 1 Mar 2005

de Groote Pascal, Helbecque Nicole, Lamblin Nicolas, Hermant Xavier, Mc Fadden Eugène, Foucher-Hossein Claude, Amouyel Philippe, Dallongeville Jean, Bauters Christophe

Abstract excerpt

Previous studies have clearly demonstrated the beneficial effect of beta-blockers in patients with stable congestive heart failure (CHF). beta-blockers improve left ventricular ejection fraction (LVEF) and reduce cardiac mortality. However, there is an interindividual variability in the response to these agents. Two studies have suggested a possible impact of some functional betaAR gene polymorphisms on the...

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PMID: 15861037
DOI: 10.1097/01213011-200503000-00001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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