Article
Beta-adrenoceptor polymorphisms and heart failure.
Trends in molecular medicine - 1 Feb 2004
Lohse Martin J
Abstract excerpt
Many polymorphisms have been described for the genes encoding the beta 1, beta 2, and alpha 2c-adrenoceptors that result in altered signaling and/or regulatory properties of the receptors. Several studies have investigated whether these properties affect the cardiovascular function of these receptors in mice or in humans, but have yielded mixed results. Some studies suggest that adrenoceptor polymorphisms might...
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