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Article

A novel polymorphism in the gene coding for the beta1-adrenergic receptor associated with survival in patients with heart failure

1 Nov 2000

Abstract excerpt

AIMS: The adrenergic nervous system is of major importance in congestive heart failure. No genetic polymorphism has previously been identified in the beta(1)-adrenergic receptor gene. The aim of this study was to find possible mutations in this gene and to relate such findings to morbidity and prognosis in heart failure. METHODS AND RESULTS: Genomic DNA was extracted from blood leukocytes from patients with...

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PMID: 11052857
DOI: 10.1053/euhj.1999.1994

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