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Article

Genetic analysis and functional characterization of polymorphisms in the human concentrative nucleoside transporter, CNT2.

Pharmacogenetics and genomics - 1 Feb 2005

Owen Ryan P, Gray Jennifer H, Taylor Travis R, Carlson Elaine J, Huang Conrad C, Kawamoto Michiko, Johns Susan J, Stryke Doug, Ferrin Thomas E, Giacomini Kathleen M

Abstract excerpt

The concentrative nucleoside transporter CNT2 (SPNT1; SLC28A2) plays a role in the absorption and disposition of naturally occurring nucleosides, as well as nucleoside analog drugs. The aim of the present study was to characterize genetic variation in SLC28A2, the gene encoding CNT2, and to functionally analyse non-synonymous variants of CNT2, as a first step towards understanding whether genetic variation in...

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PMID: 15861032
DOI: 10.1097/01213011-200502000-00004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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