Article
Functional characterization and haplotype analysis of polymorphisms in the human equilibrative nucleoside transporter, ENT2.
Drug metabolism and disposition: the biological fate of chemicals - 1 Jan 2006
Owen Ryan P, Lagpacan Leah L, Taylor Travis R, De La Cruz Melanie, Huang Conrad C, Kawamoto Michiko, Johns Susan J, Stryke Doug, Ferrin Thomas E, Giacomini Kathleen M
Abstract excerpt
The equilibrative nucleoside transporter 2 (ENT2; SLC29A2) is a bidirectional transporter that is involved in the disposition of naturally occurring nucleosides as well as a variety of anticancer and antiviral nucleoside analogs. The goal of the current study was to evaluate the function of genet...
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