Article
Identification and functional characterization of variants in human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), arising from single nucleotide polymorphisms in coding regions of the hCNT3 gene.
Pharmacogenetics and genomics - 1 Mar 2005
Damaraju Sambasivarao, Zhang Jing, Visser Frank, Tackaberry Tracey, Dufour Jennifer, Smith Kyla M, Slugoski Melissa, Ritzel Mabel W L, Baldwin Stephen A, Young James D, Cass Carol E
Abstract excerpt
INTRODUCTION: Human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), which mediates transport of purine and pyrimidine nucleosides and a variety of antiviral and anticancer nucleoside drugs, was investigated to determine if there are single nucleotide polymorphisms in the coding regions of the hCNT3 gene. METHODS AND RESULTS: Ninety-six DNA samples from Caucasians (Coriell Panel) were sequenced and...
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