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Concise Review: Pursuing Self-Renewal and Pluripotency with the Stem Cell Factor Nanog

7 May 2013

Abstract excerpt

Pluripotent embryonic stem cells and induced pluripotent stem cells hold great promise for future use in tissue replacement therapies due to their ability to self-renew indefinitely and to differentiate into all adult cell types. Harnessing this therapeutic potential efficiently requires a much deeper understanding of the molecular processes at work within the pluripotency network. The transcription factors...

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PMID: 23653415
DOI: 10.1002/stem.1384

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Concise Review: Pursuing Self-Renewal and Pluripotency with the Stem Cell Factor NanogPMID 23653415Read ↗

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Alternative splicing produces Nanog protein variants with different capacities for self-renewal and pluripotency in embryonic stem cells.Semantic proximity Read ↗

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Nanog safeguards pluripotency and mediates germline development.Semantic proximity Read ↗

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Role of Oct4 in maintaining and regaining stem cell pluripotencySemantic proximity Read ↗

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