Article
Biochemical and HIV-1 coreceptor properties of K26R, a new CCR5 Variant in China's Sichuan population.
Journal of acquired immune deficiency syndromes (1999) - 1 May 2005
Ma Liying, Dudoit Yasmine, Tran Ton, Xing Hui, Chen Jianping, Pancino Gianfranco, Bismuth Georges, Debré Patrice, Shao Yiming, Theodorou Ioannis, Capoulade-Métay Corinne
Abstract excerpt
Despite multiple exposures to HIV-1, some individuals remain uninfected. This resistance to HIV infection has been associated with homozygosity for a 32-basepair deletion in the CCR5 receptor gene. This variant is frequent in caucasians but extremely rare in Asians and Africans. Identifying variations in the CCR5 gene that affect susceptibility to HIV infection in non-caucasians is therefore of great interest. In...
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