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Article

Functional analysis of naturally occurring mutations in the open reading frame of CCR5 in HIV-infected Chinese patients and healthy controls.

Journal of acquired immune deficiency syndromes (1999) - 15 Apr 2005

Zhao Xiu-Ying, Lee Shui-Shan, Wong Ka-Hing, Chan Kenny C W, Ng Fai, Chan Chris C S, Han Dan, Yam Wing-Cheong, Yuen Kwok-Yung, Ng Mun-Hon, Zheng Bo-Jian

Abstract excerpt

We studied polymorphism of the HIV coreceptor CC chemokine receptor (CCR) 5 in 1099 Chinese adults residing in Hong Kong, including 785 HIV-negative healthy donors and 314 HIV-positive patients. Ten mutants in the CCR5 open reading frame were identified, 7 of which were nonsynonymous. The frequencies of these alleles did not show a significant difference between HIV patients and healthy controls. G106R, Delta32,...

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Share to Amino Acid Substitution
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, CCR5

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Source

Identifiers

PMID: 15793360
DOI: 10.1097/01.qai.0000151004.19128.4a

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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